Qualitative phytochemical profile, antimicrobial and hemolytic activity of ethanolic extracts from dried leaves of two varieties of Fittonia albivenis
Synopsis
The Amazon region holds a vast wealth of ancestral knowledge on medicinal plants; however, much of this ethnobotanical richness lacks scientific validation through experimental evidence. Therefore, this study evaluated the phytochemical profile, antimicrobial activity, and hemolytic effects of ethanolic extracts from dried leaves of two varieties of Fittonia albivenis (white-veined and pink-veined). Ethanolic extracts obtained through maceration, Soxhlet extraction, concentration using a rotary evaporator, and lyophilization were subjected to qualitative phytochemical screening, antimicrobial assays by agar diffusion, antifungal tests using resazurin-based microdilution, and cytotoxicity analysis via hemolysis in human erythrocytes. Results showed that the white-veined variety yielded higher extraction efficiency, whereas the pink-veined variety contained higher levels of flavonoids and alkaloids. In antimicrobial assays, the pink-veined variety exhibited strong inhibition against Staphylococcus aureus. Both extracts demonstrated dose-dependent inhibition against Fusarium oxysporum and Aspergillus fumigatus at higher concentrations, while hemolytic activity was minimal. These findings support the therapeutic potential of F. albivenis as a source of natural bioactive compounds.
Published
April 3, 2026
Categories
Copyright (c) 2026 Zulay Marina Niño Ruiz, Laura Inés Salazar Cotugno (Coordinador de obra); Patricia Yissel Dávalos Cerrón, Azucena Chanatasig, Felipe Cerrera, Andrea Carolina Palacios Rosado, Mateo Patricio Sánchez Sanaguano, Liliana Paulina Lalaleo Córdova, William Calero Cáceres, Santiago Casado, Joshua Pazmiño, Jaime Martí-Herrero, Rocio Cecibel Jiménez Paute, Kevin Campaña, Elena Coyago-Cruz, Andrea Hidalgo-Dávila, Lizbeth Alpusig-Guanoluisa, Belén Apolo, Felipe Rivera-Rueda, Yerovi Sánchez-Arias, Karen Marcella García, Rubianith Suárez, Harol Smith Daza, Geovanna Tafurt, Duverney de Jesús Chaverra, Edita Valle, Evelyn Oña, Mishel Calero, Jonathan Liria, Andrés Sebastian Calderón Velasco, Roque Rivas-Párraga, Inti Llumiquinga, Ana Bravo, Julio Rea, Máximo Moreira, Oscar Vivanco, Nicole Jara, Lilibeth Carrión, Stefanía Cevallos, Paulo Herrera, Esteban Patricio Romero Valladares, Ana Paula Rosero-Jácome, Eliza Jara-Negrete, Gabriel Picón Nava, Nelly Paredes, Wilfredo Ramiro Franco, Wilmer Shiguango, Willin Álvarez, Juan Ponce, Jessica Sánchez, Christian Israel Andrade Romero, Alexandra Vargas, David Sanchez, Negover Briñez, Byron García, Dennis Tomalá, Mery Ramirez, Jenny Rodríguez, Paúl Tufiño Mateus, Enrique Laaz, Willan Revelo, Cecilia Puertas, Juan Andrés Guadamud, Karina Olalla-Tacuri , Darwin Omar Yánez Avalos, Diana Callejas, Sara Álvarez, John Mauricio Castillo Torres, Edith Pamela Tapia Pruna, Daniela Endara, Carolina Castro, Silvia Alejandra Llerena Gordillo, Kevin Stwart Tulcanaza Ruiz, Noroska G.S. Mogollón, Melany Ochoa, María Cristina Peñuela, Jimmy Yumbo, Enith Yánez, Carolina Ñacato, Samira Lluno, Henry Conteron, Pedro Cadena, Corina Campos, Oswaldo Guzman, Micaela Campos, Cindy Vera, Dayana Vera, Christian Coral, Bruce Tumbaco, María Soledad Solorzano, Bryan Valencia, José Sebastián Araujo Soria, Sandra Torres, Enzo Loor, Oscar Ayala, Darwin Rosero, Amparo Condor, Luis Cáceres, Miguel Flores, Elena Ulcuango, Nicole Pilco, David Galarza, Mishell Cabrera, Julieth Chancay, Paola Soto, David Portillo, Diana Cisneros, José Aguirre-Déleg, Pablo Maita-Zambrano, Aimee Delgado-Cruz, Myrian Larco, María Soledad Salazar, María Susana Grijalva, Viviana Stefanía Cárdenas Loor, Mónica Dazzini Langdon, Sheila Tobar Vallejo, Vinicio Velásquez Zambrano, Juan Carlos Soria Aguas (Autor de capítulo)
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How to Cite
Qualitative phytochemical profile, antimicrobial and hemolytic activity of ethanolic extracts from dried leaves of two varieties of Fittonia albivenis. (2026). In III International Congress of Biotechnology and Neotropical Ecosystems. Editorial Unión Científica. https://doi.org/10.63804/CIBEN.25.sioh.e3
