Qualitative phytochemical profile, antimicrobial and hemolytic activity of ethanolic extracts from dried leaves of two varieties of Fittonia albivenis

Authors

Daniela Endara
Universidad Regional Amazónica, Ikiam
https://orcid.org/0009-0001-2286-0656
Carolina Castro
Universidad Regional Amazónica, Ikiam
https://orcid.org/0009-0008-5777-4636
Silvia Alejandra Llerena Gordillo
Grupo de investigación Ecosistemas Tropicales y cambio Global. Universidad Regional Amazónica, Ikiam
https://orcid.org/0000-0002-0491-530X
Mateo Salazar
Laboratorio de Investigación en Citogenética y Biomoléculas de Anfibios (LICBA), Centro de Investigación para la Salud en América Latina—CISeAL, Facultad de Ciencias Exactas y Naturales, Pontificia Universidad Católica del Ecuador
https://orcid.org/0000-0002-1225-7140
Miryan Rivera
Laboratorio de Investigación en Citogenética y Biomoléculas de Anfibios (LICBA), Centro de Investigación para la Salud en América Latina—CISeAL, Facultad de Ciencias Exactas y Naturales, Pontificia Universidad Católica del Ecuador
https://orcid.org/0000-0002-9944-7130

Synopsis

The Amazon region holds a vast wealth of ancestral knowledge on medicinal plants; however, much of this ethnobotanical richness lacks scientific validation through experimental evidence. Therefore, this study evaluated the phytochemical profile, antimicrobial activity, and hemolytic effects of ethanolic extracts from dried leaves of two varieties of Fittonia albivenis (white-veined and pink-veined). Ethanolic extracts obtained through maceration, Soxhlet extraction, concentration using a rotary evaporator, and lyophilization were subjected to qualitative phytochemical screening, antimicrobial assays by agar diffusion, antifungal tests using resazurin-based microdilution, and cytotoxicity analysis via hemolysis in human erythrocytes. Results showed that the white-veined variety yielded higher extraction efficiency, whereas the pink-veined variety contained higher levels of flavonoids and alkaloids. In antimicrobial assays, the pink-veined variety exhibited strong inhibition against Staphylococcus aureus. Both extracts demonstrated dose-dependent inhibition against Fusarium oxysporum and Aspergillus fumigatus at higher concentrations, while hemolytic activity was minimal. These findings support the therapeutic potential of F. albivenis as a source of natural bioactive compounds.

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Published

May 25, 2026

How to Cite

Qualitative phytochemical profile, antimicrobial and hemolytic activity of ethanolic extracts from dried leaves of two varieties of Fittonia albivenis. (2026). In III International Congress of Biotechnology and Neotropical Ecosystems (p. sioh.e3). Editorial Unión Científica. https://doi.org/10.63804/CIBEN.25.sioh.e3